Fasudil alleviates LPS-induced lung injury by restoring aquaporin 5 expression and inhibiting inflammation in lungs

Fasudil, a selective rho kinase (ROCK) inhibitor, has been reported to play a beneficial role in systemic?inflammation?in acute?lung injury, but its mechanism for ameliorating pulmonary edema and inflammation remains unclear. Using hematoxylin-and-eosin (H&E) staining, immunohistochemistry, enzy...

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Detalles Bibliográficos
Autores principales: Wang, Jingjing, Kong, Hui, Xu, Jian, Wang, Yanli, Wang, Hong, Xie, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551422/
https://www.ncbi.nlm.nih.gov/pubmed/28963443
http://dx.doi.org/10.7555/JBR.31.20170024

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