Cargando…
Evaluation of critical design parameters for RT‐qPCR‐based analysis of multiple dUTPase isoform genes in mice
The coupling of nucleotide biosynthesis and genome integrity plays an important role in ensuring faithful maintenance and transmission of genetic information. The enzyme dUTPase is a prime example of such coupling, as it generates dUMP for thymidylate biosynthesis and removes dUTP for synthesis of u...
Autores principales: | Rácz, Gergely A., Nagy, Nikolett, Gál, Zoltán, Pintér, Tímea, Hiripi, László, Vértessy, Beáta G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551494/ https://www.ncbi.nlm.nih.gov/pubmed/31077566 http://dx.doi.org/10.1002/2211-5463.12654 |
Ejemplares similares
-
CRISPR/Cas9-Mediated Knock-Out of dUTPase in Mice Leads to Early Embryonic Lethality
por: Pálinkás, Hajnalka Laura, et al.
Publicado: (2019) -
Life without dUTPase
por: Kerepesi, Csaba, et al.
Publicado: (2016) -
The dUTPase Enzyme Is Essential in Mycobacterium smegmatis
por: Pecsi, Ildiko, et al.
Publicado: (2012) -
Calpain-Catalyzed Proteolysis of Human dUTPase Specifically Removes the Nuclear Localization Signal Peptide
por: Bozóky, Zoltán, et al.
Publicado: (2011) -
Structural model of human dUTPase in complex with a novel proteinaceous inhibitor
por: Nyíri, Kinga, et al.
Publicado: (2018)