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Wave front analysis for enhanced time-domain beamforming of point-like targets in optoacoustic imaging using a linear array

Using linear array transducers in combination with state-of-the-art multichannel electronics allows to perform optoacoustic imaging with frame rates only limited by the laser pulse repetition frequency and the acoustic time of flight. However, characteristic image artefacts resulting from the limite...

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Detalles Bibliográficos
Autores principales: Fournelle, Marc, Bost, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551558/
https://www.ncbi.nlm.nih.gov/pubmed/31194149
http://dx.doi.org/10.1016/j.pacs.2019.04.002
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author Fournelle, Marc
Bost, Wolfgang
author_facet Fournelle, Marc
Bost, Wolfgang
author_sort Fournelle, Marc
collection PubMed
description Using linear array transducers in combination with state-of-the-art multichannel electronics allows to perform optoacoustic imaging with frame rates only limited by the laser pulse repetition frequency and the acoustic time of flight. However, characteristic image artefacts resulting from the limited view and a lower SNR when compared to systems based on single-element focused transducers represent a burden for the clinical acceptance of the technology. In this paper, we present a new method for the improvement of image quality based on the analysis of the signal amplitudes along summation curves during the delay-and-sum beamforming process (DAS). The algorithm compares amplitude distributions along wave fronts with theoretical patterns from optoacoustic point sources. The method was validated on simulated and experimental phantom as well as in-vivo data. An improvement of the lateral resolution by more than a factor of two when comparing conventional DAS and our approach could be shown (numeric and experimental phantom data). For instance, on experimental data from a wire phantom, a PSF in the range of 0.18–0.22 mm was obtained with our approach against 0.48 mm for standard DAS. Furthermore, the SNR of a subcutaneous vessel 2.5 mm below the skin surface was improved by about 30 dB when compared to standard DAS.
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spelling pubmed-65515582019-06-10 Wave front analysis for enhanced time-domain beamforming of point-like targets in optoacoustic imaging using a linear array Fournelle, Marc Bost, Wolfgang Photoacoustics Research Article Using linear array transducers in combination with state-of-the-art multichannel electronics allows to perform optoacoustic imaging with frame rates only limited by the laser pulse repetition frequency and the acoustic time of flight. However, characteristic image artefacts resulting from the limited view and a lower SNR when compared to systems based on single-element focused transducers represent a burden for the clinical acceptance of the technology. In this paper, we present a new method for the improvement of image quality based on the analysis of the signal amplitudes along summation curves during the delay-and-sum beamforming process (DAS). The algorithm compares amplitude distributions along wave fronts with theoretical patterns from optoacoustic point sources. The method was validated on simulated and experimental phantom as well as in-vivo data. An improvement of the lateral resolution by more than a factor of two when comparing conventional DAS and our approach could be shown (numeric and experimental phantom data). For instance, on experimental data from a wire phantom, a PSF in the range of 0.18–0.22 mm was obtained with our approach against 0.48 mm for standard DAS. Furthermore, the SNR of a subcutaneous vessel 2.5 mm below the skin surface was improved by about 30 dB when compared to standard DAS. Elsevier 2019-05-25 /pmc/articles/PMC6551558/ /pubmed/31194149 http://dx.doi.org/10.1016/j.pacs.2019.04.002 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Article
Fournelle, Marc
Bost, Wolfgang
Wave front analysis for enhanced time-domain beamforming of point-like targets in optoacoustic imaging using a linear array
title Wave front analysis for enhanced time-domain beamforming of point-like targets in optoacoustic imaging using a linear array
title_full Wave front analysis for enhanced time-domain beamforming of point-like targets in optoacoustic imaging using a linear array
title_fullStr Wave front analysis for enhanced time-domain beamforming of point-like targets in optoacoustic imaging using a linear array
title_full_unstemmed Wave front analysis for enhanced time-domain beamforming of point-like targets in optoacoustic imaging using a linear array
title_short Wave front analysis for enhanced time-domain beamforming of point-like targets in optoacoustic imaging using a linear array
title_sort wave front analysis for enhanced time-domain beamforming of point-like targets in optoacoustic imaging using a linear array
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551558/
https://www.ncbi.nlm.nih.gov/pubmed/31194149
http://dx.doi.org/10.1016/j.pacs.2019.04.002
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