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SAT-247 Two-Year Treatment with Metformin during Puberty Is Associated with Improvements in Body Composition, but Not in Insulin Sensitivity or β-Cell Function in Obese Youth
Background. The incidence of youth-onset type 2 diabetes in obese youth is tightly linked with the physiologic insulin resistance of puberty. The Health Influences of Puberty (HIP) Study was a placebo-controlled trial of metformin to test whether metformin mitigates the decrease in insulin sensitivi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551647/ http://dx.doi.org/10.1210/js.2019-SAT-247 |