SAT-247 Two-Year Treatment with Metformin during Puberty Is Associated with Improvements in Body Composition, but Not in Insulin Sensitivity or β-Cell Function in Obese Youth

Background. The incidence of youth-onset type 2 diabetes in obese youth is tightly linked with the physiologic insulin resistance of puberty. The Health Influences of Puberty (HIP) Study was a placebo-controlled trial of metformin to test whether metformin mitigates the decrease in insulin sensitivi...

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Detalles Bibliográficos
Autores principales: Kelsey, Megan, Pyle, Laura, Allison, Hilkin, Van Pelt, Rachael, Zeitler, Philip, Nadeau, Kristen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Pediatric Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551647/
http://dx.doi.org/10.1210/js.2019-SAT-247

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