Fumarase mediates transcriptional response to nutrient stress

Limited supply of nutrient normally causes cell growth arrest. Our recent study (Nat Cell Biol. (7):833-843) shows that fumarase (FH), a key enzyme responsible for the conversion between fumarate and malate in tricarboxylic acid cycle, is importantly involved in the cellular response to nutrient con...

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Detalles Bibliográficos
Autores principales: Zhao, Qin, Jiang, Yuhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2017
Materias:
Microreview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551652/
https://www.ncbi.nlm.nih.gov/pubmed/31225435
http://dx.doi.org/10.15698/cst2017.10.107
Descripción
Sumario:Limited supply of nutrient normally causes cell growth arrest. Our recent study (Nat Cell Biol. (7):833-843) shows that fumarase (FH), a key enzyme responsible for the conversion between fumarate and malate in tricarboxylic acid cycle, is importantly involved in the cellular response to nutrient condition.

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