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Targeting LRH-1/NR5A2 to treat type 1 diabetes mellitus

Type 1 diabetes mellitus (T1DM) is defined as an autoimmune disease that targets the selective destruction of islet insulin-producing beta cells by infiltrating immune cells (insulitis). As a result, the organism is no longer able to produce insulin and develops hyperglycaemia and, if untreated, dea...

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Detalles Bibliográficos
Autores principales: Cobo-Vuilleumier, Nadia, Lorenzo, Petra I., Gauthier, Benoit R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551680/
https://www.ncbi.nlm.nih.gov/pubmed/31225479
http://dx.doi.org/10.15698/cst2018.06.140