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SAT-159 Hltf-Deletion Causes Immune Destruction of Pancreatic Beta Cells during Development
Immune destruction that causes the failure of β cell insulin secretion in type I diabetes (T1D) results from an imbalance in genetic, epigenetic and environmental factors that can begin in utero. A key unanswered question is how and why immune cells are targeted to specifically destroy insulin-produ...
Autores principales: | Kaur, Gurvinder, Helmer, Rebecca, Dufour, Jannette, Chilton, Beverly |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551699/ http://dx.doi.org/10.1210/js.2019-SAT-159 |
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