MST kinases in innate immune signaling

The mammalian STE20-like (MST) protein kinases are composed of MST1, MST2, MST3, MST4 and YSK1. They play crucial roles in cell growth, migration, polarity and apoptosis. Dysfunction of these kinases often leads to diseases. MST kinases are extensively involved in development and function of immune...

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Detalles Bibliográficos
Autores principales: Shi, Zhubing, Zhou, Zhaocai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551840/
https://www.ncbi.nlm.nih.gov/pubmed/31225446
http://dx.doi.org/10.15698/cst2018.01.119
Descripción
Sumario:The mammalian STE20-like (MST) protein kinases are composed of MST1, MST2, MST3, MST4 and YSK1. They play crucial roles in cell growth, migration, polarity and apoptosis. Dysfunction of these kinases often leads to diseases. MST kinases are extensively involved in development and function of immune system. Here, we review recent progresses on the regulatory function of MST kinases in innate immune signaling.

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