MST kinases in innate immune signaling

The mammalian STE20-like (MST) protein kinases are composed of MST1, MST2, MST3, MST4 and YSK1. They play crucial roles in cell growth, migration, polarity and apoptosis. Dysfunction of these kinases often leads to diseases. MST kinases are extensively involved in development and function of immune...

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Detalles Bibliográficos
Autores principales: Shi, Zhubing, Zhou, Zhaocai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551840/
https://www.ncbi.nlm.nih.gov/pubmed/31225446
http://dx.doi.org/10.15698/cst2018.01.119
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author Shi, Zhubing
Zhou, Zhaocai
author_facet Shi, Zhubing
Zhou, Zhaocai
author_sort Shi, Zhubing
collection PubMed
description The mammalian STE20-like (MST) protein kinases are composed of MST1, MST2, MST3, MST4 and YSK1. They play crucial roles in cell growth, migration, polarity and apoptosis. Dysfunction of these kinases often leads to diseases. MST kinases are extensively involved in development and function of immune system. Here, we review recent progresses on the regulatory function of MST kinases in innate immune signaling.
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spelling pubmed-65518402019-06-20 MST kinases in innate immune signaling Shi, Zhubing Zhou, Zhaocai Cell Stress Review The mammalian STE20-like (MST) protein kinases are composed of MST1, MST2, MST3, MST4 and YSK1. They play crucial roles in cell growth, migration, polarity and apoptosis. Dysfunction of these kinases often leads to diseases. MST kinases are extensively involved in development and function of immune system. Here, we review recent progresses on the regulatory function of MST kinases in innate immune signaling. Shared Science Publishers OG 2017-12-23 /pmc/articles/PMC6551840/ /pubmed/31225446 http://dx.doi.org/10.15698/cst2018.01.119 Text en Copyright: © 2017 Shi and Zhou https://creativecommons.org/licenses/by/4.0/ This is an open-access article released under the terms of the Creative Commons Attribution (CC BY) license, which allows the unrestricted use, distribution, and reproduction in any medium, provided the original author and source are acknowledged.
spellingShingle Review
Shi, Zhubing
Zhou, Zhaocai
MST kinases in innate immune signaling
title MST kinases in innate immune signaling
title_full MST kinases in innate immune signaling
title_fullStr MST kinases in innate immune signaling
title_full_unstemmed MST kinases in innate immune signaling
title_short MST kinases in innate immune signaling
title_sort mst kinases in innate immune signaling
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551840/
https://www.ncbi.nlm.nih.gov/pubmed/31225446
http://dx.doi.org/10.15698/cst2018.01.119
work_keys_str_mv AT shizhubing mstkinasesininnateimmunesignaling
AT zhouzhaocai mstkinasesininnateimmunesignaling

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