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Novel role of the SIRT4-OPA1 axis in mitochondrial quality control
Mammalian sirtuins are fundamental regulators of a plethora of cellular functions, including gene expression, proliferation, metabolism, and ultimatively cellular aging and organismal life-span. The mitochondrial sirtuin SIRT4 acts as metabolic tumor suppressor and is down-regulated in many cancer t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Shared Science Publishers OG
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551841/ https://www.ncbi.nlm.nih.gov/pubmed/31225445 http://dx.doi.org/10.15698/cst2018.01.118 |