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An integrated quantitative structure and mechanism of action-activity relationship model of human serum albumin binding
BACKGROUND: Traditional quantitative structure-activity relationship models usually neglect the molecular alterations happening in the exposed systems (the mechanism of action, MOA), that mediate between structural properties of compounds and phenotypic effects of an exposure. RESULTS: Here, we prop...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551915/ https://www.ncbi.nlm.nih.gov/pubmed/31172382 http://dx.doi.org/10.1186/s13321-019-0359-2 |