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SAT-042 Pituitary Expression Of Isl1 Prevents Ectopic, Foxa1 And Foxj1 Mediated Differentiation Of Progenitors Into Rathke’S Cleft Cysts

Islet 1 (ISL1) is a LIM homeodomain transcription factor expressed in the developing pituitary gland. Its expression overlaps with the progenitor markers SOX2 and PROP1 and with the differentiation markers NR5A1 and CGA, or alpha-subunit. We conditionally knocked out Isl1 using several Cre recombina...

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Detalles Bibliográficos
Autores principales:	Camper, Sally, Brinkmeier, Michelle, Bando, Hironori, Fujio, Shingo, Yashimoto, Koji, Camarano, Adriana, de Souza, Flavio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2019
Materias:	Non-Steroid Hormone Signaling
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551927/ http://dx.doi.org/10.1210/js.2019-SAT-042

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