Cargando…

SAT-566 Cofilin Is a Mediator of RET-Promoted Medullary Thyroid Carcinoma Cell Migration, Invasion and Proliferation

Medullary thyroid carcinoma (MTC) is a rare neuroendocrine tumor that originates from parafollicular thyroid C cells, accounting for 5% -10% of thyroid cancers. In all inherited cases of MTC, and in about 40% of sporadic cases, activating mutations of the receptor tyrosine kinase proto-oncogene RET...

Descripción completa

Detalles Bibliográficos
Autores principales:	Peverelli, Erika, GIARDINO, ELENA, CATALANO, ROSA, BARBIERI, ANNAMARIA, Treppiedi, Donatella, MANGILI, FEDERICA, Spada, Anna, Arosio, Maura, Mantovani, Giovanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2019
Materias:	Thyroid
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551961/ http://dx.doi.org/10.1210/js.2019-SAT-566

Ejemplares similares

SAT-312 Beta-Arrestin 2 Is Required for Dopamine Receptor Type 2 Inhibitory Effects on Akt Phosphorylation and Cell Proliferation in Pituitary Tumors
por: Mangili, Federica, et al.
Publicado: (2020)

MON-465 SST2 Trafficking Through The Cytoskeleton: Role Of Scaffolding Proteins Filamin A And β-arrestin 2
por: Treppiedi, Donatella, et al.
Publicado: (2019)

Stem Cells in Pituitary Tumors: Experimental Evidence Supporting Their Existence and Their Role in Tumor Clinical Behavior
por: Mantovani, Giovanna, et al.
Publicado: (2019)

SUN-213 The Role of Filamin A (FLNA) in the Regulation of Insulin-Like Growth Factor System in Adrenocortical Carcinomas
por: Peverelli, Erika, et al.
Publicado: (2020)

A Novel Mechanism Regulating Dopamine Receptor Type 2 Signal Transduction in Pituitary Tumoral Cells: The Role of cAMP/PKA-Induced Filamin A Phosphorylation
por: Mangili, Federica, et al.
Publicado: (2021)

SAT566 A Rare Case Of Aggressive Anaplastic Thyroid Presenting As Thyrotoxicosis
por: Al-Juboori, Amenah, et al.
Publicado: (2023)

Role of filamin A in the pathogenesis of neuroendocrine tumors and adrenal cancer
por: Treppiedi, Donatella, et al.
Publicado: (2022)

TMPRSS2 Expression and Activity Modulation by Sex-Related Hormones in Lung Calu-3 Cells: Impact on Gender-Specific SARS-CoV-2 Infection
por: Treppiedi, Donatella, et al.
Publicado: (2022)

Dimerization of GPCRs: Novel insight into the role of FLNA and SSAs regulating SST(2) and SST(5) homo- and hetero-dimer formation
por: Treppiedi, Donatella, et al.
Publicado: (2022)

SAT540 A Case of Simultaneous Medullary Thyroid Cancer (MTC) And Papillary Thyroid Cancer (PTC) In a Patient With Germline RET Mutation
por: Vaghasia, Nishit, et al.
Publicado: (2023)

DRD2 Agonist Cabergoline Abolished the Escape Mechanism Induced by mTOR Inhibitor Everolimus in Tumoral Pituitary Cells
por: Mangili, Federica, et al.
Publicado: (2022)

PMON171 DRD2 Agonist Cabergoline Abolished the Escape Mechanism Induced by mTOR Inhibitor Everolimus in Pituitary Neuroendocrine Tumoral Cells
por: Mangili, Federica, et al.
Publicado: (2022)

Genetic Profiling of a Cohort of Italian Patients with ACTH-Secreting Pituitary Tumors and Characterization of a Novel USP8 Gene Variant
por: Treppiedi, Donatella, et al.
Publicado: (2021)

SUN-LB75 The Anti-Tumor Activity of the Selective Ret Inhibitor Selpercatinib (LOXO-292) in Medullary Thyroid Cancer Is Independent of the Specific RET Mutation
por: Cabanillas, Maria E, et al.
Publicado: (2020)

MON-562 Retrospective Analysis of Medullary Thyroid Carcinoma: Comparison between Individuals with and without RET Germline Mutation
por: Costa, Cláudia, et al.
Publicado: (2019)

LBODP099 A Young Patient With Undifferentiated And Advanced Medullary Thyroid Carcinoma With Negative RET - CASE REPORT
por: Fraga, Lais Oliveira Teles, et al.
Publicado: (2022)

SAT521 Predictive Value of Tumor Volumetrics in Patients with Medullary Thyroid Cancer
por: Behairy, Noha, et al.
Publicado: (2023)

A β-Arrestin 2-Biased Dopamine Receptor Type 2 (DRD2) Agonist Is More Efficacious Than Cabergoline in Reducing Cell Proliferation in PRL-Secreting but Not in Non-Functioning Pituitary Tumor Cells
por: Di Muro, Genesio, et al.
Publicado: (2023)

SUN-566 Sspontaneous Oscillating Hypothyroidism and Hyperthyroidism: A Rare Autoimmune Entity
por: Ghrewati, Moutaz, et al.
Publicado: (2019)

Molecular mechanisms involved in somatostatin receptor regulation in corticotroph tumors: the role of cytoskeleton and USP8 mutations
por: Peverelli, Erika, et al.
Publicado: (2022)

P720R USP8 Mutation Is Associated with a Better Responsiveness to Pasireotide in ACTH-Secreting PitNETs
por: Treppiedi, Donatella, et al.
Publicado: (2022)

Dopamine and Somatostatin Analogues Resistance of Pituitary Tumors: Focus on Cytoskeleton Involvement
por: Peverelli, Erika, et al.
Publicado: (2015)

SAT560 A Case of Medullary Thyroid Carcinoma with Increasing Carcinoembryonic Antigen and Stable Calcitonin Levels
por: Youssef, Kerolos N, et al.
Publicado: (2023)

SAT535 ANKRD26-RET Fusion Positive Metastatic Papillary Thyroid Carcinoma - Advanced Presentation of a Rare Mutation
por: Hashmi, Hiba, et al.
Publicado: (2023)

SAT568 A Case Of Medullary Thyroid Cancer Associated With Cutaneous Metastasis: A Rare And Aggressive Presentation
por: Vaghasia, Nishit, et al.
Publicado: (2023)

SAT-585 Presence of Metastatic Medullary Thyroid Cancer without a Distinct Thyroid Nodule: A Diagnostic Challenge
por: Xhikola, Majlinda, et al.
Publicado: (2019)

SAT561 Pathogenic RET V804M Germline Variant Without Clinical Manifestations Of Multiple Endocrine Neoplasia Type 2 In An Elderly Male
por: Ghosh, Raisa, et al.
Publicado: (2023)

SAT555 Utility of (18)F-DOPA PET/CT in the Diagnosis of Medullary Thyroid Cancer in a Patient with Multiple Endocrine Neoplasia Type 2B
por: Varghese, Diana Grace, et al.
Publicado: (2023)

MON-509 RET Mutations in the MEN1 Syndrome: Is It an Innocent Bystander?
por: Rais, Nadeem M, et al.
Publicado: (2020)

MON-566 Early Diagnosis of Lymph Node Metastases by Serum Tg and Neck Ultrasonography, and Long Term Follow Up After Radioiodine and/or Surgical Treatment in Patients with Papillary or Follicular Thyroid Cancer.
por: Fallahi, Poupak, et al.
Publicado: (2019)

SAT-493 A Case of Profound Hypothyroidism Secondary to Immune Check Point Inhibitors
por: Tun, Yin Nwe, et al.
Publicado: (2020)

SAT-611 Abdominal Goiter
por: Bedoya, Pablo, et al.
Publicado: (2019)

MON-450 Prophylactic Thyroidectomy in a Patient with Codon 891 Mutation of the RET Proto-Oncogene
por: Swami, Janya, et al.
Publicado: (2020)

SAT-494 An Unusual Presentation of Hypothyroidism
por: Sukumaran, Anju
Publicado: (2020)

SAT-509 Sudden Onset of Malabsorption
por: Mroueh, Gabriela, et al.
Publicado: (2020)

Medullary Carcinoma of Thyroid Due to GLP-1 Receptor Agonist
por: Vemula, Hasitha, et al.
Publicado: (2021)

SAT-576 Lyme Disease Associated Thyroiditis
por: Deol, Navreet, et al.
Publicado: (2019)

SAT-624 Amiodarone-Induced Myxedema Coma
por: Rana, Sanah, et al.
Publicado: (2019)

SAT-LB87 Golimumab Induced Thyroiditis
por: Mai, Mo M, et al.
Publicado: (2020)

SAT-476 Alemtuzumab Induced Graves Disease
por: Caputi, Rafael C, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_03tar6h88292vckdjm7od905fb