SAT-LB064 Mitotane Induces Autophagy: A Mechanism to Promote Chemoresistance in Adrenocortical Carcinoma

Adrenocortical carcinoma (ACC) is an orphan malignancy with dismal survival rates. Although recent large genomic studies have shed insight into underlying molecular mechanisms, there are currently no targeted therapies available. Autophagy is an important cellular process to promote survival in a lo...

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Detalles Bibliográficos
Autores principales: Tompkins, Kenneth, Towers, Christina, Kar, Adwitiya, Zhang, Yu, Kiseljak-Vassiliades, Katja, Thorburn, Andrew, Wierman, Margaret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Adrenal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551990/
http://dx.doi.org/10.1210/js.2019-SAT-LB064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551990/
http://dx.doi.org/10.1210/js.2019-SAT-LB064

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