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SAT-LB064 Mitotane Induces Autophagy: A Mechanism to Promote Chemoresistance in Adrenocortical Carcinoma
Adrenocortical carcinoma (ACC) is an orphan malignancy with dismal survival rates. Although recent large genomic studies have shed insight into underlying molecular mechanisms, there are currently no targeted therapies available. Autophagy is an important cellular process to promote survival in a lo...
Autores principales: | Tompkins, Kenneth, Towers, Christina, Kar, Adwitiya, Zhang, Yu, Kiseljak-Vassiliades, Katja, Thorburn, Andrew, Wierman, Margaret |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551990/ http://dx.doi.org/10.1210/js.2019-SAT-LB064 |
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