SAT-LB056 Is AIP a Tumor Suppressor or an Oncogene? AIP as a Novel Regulator of the Oncogene BCL6 in Diffuse Large B Cell Lymphoma

Background: Heterozygous germline loss-of-function mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene are usually associated with acromegaly or gigantism due to a young-onset somatotropinoma. AIP functions as a tumor suppressor gene in the pituitary, while its role in other tu...

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Detalles Bibliográficos
Autores principales: BARRY, SAYKA, Sun, Dijue, Stopka-Farooqui, Urszula, Aksoy, Ezra, Parsonage, Gregory, Vossenkamper, Anna, Capasso, Melania, Wan, Xinyu, Norris, Sherine, Marshall, Jennifer, Clear, Andrew, Gribben, John, MacDonald, Thomas, Buckley, Christopher, Korbonits, Marta, Haworth, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Tumor Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551993/
http://dx.doi.org/10.1210/js.2019-SAT-LB056

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