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SAT-421 Cell-Specific Ablation of GnRH Neurons Using Kisspeptin-Saporin in the Preoptic Area of Sheep, but Not Mice

Sheep have been a useful preclinical model for the exploration of the role of kisspeptin and its receptor, KISS1R, in the control of pulsatile section of gonadotropin releasing hormone (GnRH). However, lack of reagents to interrogate KISS1R neurons in sheep has limited progress in this species. To a...

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Detalles Bibliográficos
Autores principales:	Porter, Danielle, Moore, Aleisha, Goodman, Robert, Hileman, Stanley, Coolen, Lique, Lehman, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2019
Materias:	Neuroendocrinology and Pituitary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551997/ http://dx.doi.org/10.1210/js.2019-SAT-421

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