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SAT-567 Mutational Profile of Hurthle Cell Carcinomas: Recurrent Mutations in Wnt/β-catenin Pathway Genes

Hürthle cell carcinomas (HCC) genomic characterization is evolving. Recent studies identified recurrent alterations in a few genes, chromosomal losses and mitochondrial DNA mutations. Gene expression studies demonstrated distinct profiles of PI3K-AKT-mTOR and Wnt/β-catenin pathways in widely invasiv...

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Detalles Bibliográficos
Autores principales:	Santana, Nathalie, Lerario, Antonio, Schmerling, Claudia, Alves, Venancio, Guazzelli, Isabel, Frazzatto, Eliana, Hoff, Ana, Marui, Suemi, Danilovic, Debora
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2019
Materias:	Thyroid
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552058/ http://dx.doi.org/10.1210/js.2019-SAT-567

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