SAT-520 The Effects Of AKAP13 On Osteogenesis By Modulation Of RhoA And Wnt Signaling

[Introduction] AKAP13 (Protein Kinase A Anchoring Protein 13) is a guanine nucleotides exchange factor (GEF) that activates RhoA as well as a scaffold protein integrating multiple signaling cascades. Previous study has shown that Akap13 hetero knockout mice develop osteoporotic changes and result in...

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Detalles Bibliográficos
Autores principales: Ishida, Akiko, Nakayama, Akitoshi, Koide, Hisashi, Tatsuno, Ichiro, Tanaka, Tomoaki, Yokote, Kotaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Bone and Mineral Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552077/
http://dx.doi.org/10.1210/js.2019-SAT-520

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