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SAT-329 Novel Dehydroepiandrosterone Derivatives Inhibiting Metastatic Prostate Cancer Cell Proliferation

Abstract: Metastatic prostate tumor cells mainly express type 1 5α-reductase and have been linked to antiandrogenic resistant prostate cancers. However, the isozyme of type 2 5α-reductase is mostly expressed in normal prostate epithelial cells and non-metastatic cancer cells of the prostate. Therefo...

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Detalles Bibliográficos
Autores principales: Cabeza, Marisa, Bautista, Lucero, Heuze, Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552093/
http://dx.doi.org/10.1210/js.2019-SAT-329