Cargando…
SAT-172 Continuous, Prolonged Treatment with the Oligonucleotide IMT504 in Diabetic NOD Mice Greatly Improves All Parameters of the Diabetic Condition
We have shown that the immunomodulatory oligonucleotide IMT504 (IMT) induces a marked recovery of single-dose streptozotocin (STZ)-induced toxic diabetes in rats that correlates with early expression of progenitor cell markers but without altering immune parameters. IMT also improves the diabetic co...
Autores principales: | Bianchi, Stefania, Lavignolle Heguy, María, Montaner, Alejandro, Libertun, Carlos, Lux-Lantos, Victoria, Bianchi, Maria |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552137/ http://dx.doi.org/10.1210/js.2019-SAT-172 |
Ejemplares similares
-
SAT-165 Does Oligodeoxynucleotide IMT504 Have Any Effect On Beta Cells? A Preliminary Study On MIN6B1 Cell Line
por: Converti, Ayelén, et al.
Publicado: (2019) -
SAT035 Oligonucleotide IMT504 Markedly Improves Metabolic Sindrome And Type 2 Diabetes In High-Fat Diet Fed Mice
por: Domé, Laila, et al.
Publicado: (2023) -
IMT504 protects beta cells against apoptosis and maintains beta cell identity, without modifying proliferation
por: Converti, Ayelén, et al.
Publicado: (2023) -
Immunomodulatory oligonucleotide IMT504: Effects on mesenchymal stem cells as a first-in-class immunoprotective/immunoregenerative therapy
por: Zorzopulos, Jorge, et al.
Publicado: (2017) -
SAT-670 The Perfect Storm for Diabetic Ketoacidosis
por: Abushamat, Layla A, et al.
Publicado: (2020)