SAT-326 INPP4B Suppresses Prostate Inflammation And Protects Mice Fed With High-fat Diet From The Development Of Prostate Intraepithelial Neoplasia

High fat diet leads to obesity, chronic inflammation, accelerated prostate cancer progression, and decreased survival. INPP4B, a dual specificity phosphatase, is a tumor suppressor which opposes Akt and PKC signaling pathways activated in response to obesity and prostate cancer progression. Previous...

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Detalles Bibliográficos
Autores principales: Zhang, Manqi, Vasquez, Judy, Kaftanovskaya, Elena, Agoulnik, Alexander, Vacher, Jean, Ittmann, Michael, Agoulnik, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Tumor Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552162/
http://dx.doi.org/10.1210/js.2019-SAT-326

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