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SAT-530 Establishment of a Glucocorticoid (GC) Regimen to Induce Both Growth Retardation and Osteoporosis in C57BL/10 Muscular Dystrophy Mouse Models

Glucocorticoids (GCs) are associated with many adverse effects including osteoporosis and growth retardation. These are particular problems in Duchenne muscular dystrophy (DMD) where GCs form the mainstay of treatment. The mechanisms that underlie the undesirable effects of GCs on skeletal developme...

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Detalles Bibliográficos
Autores principales: Wood, Claire, Wong, Jarod Sze Choong, Straub, Volker, Ahmed, S, Farquharson, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552208/
http://dx.doi.org/10.1210/js.2019-SAT-530