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SAT-045 Transient Developmental Hypothyroidism Results in Dysregulation of Neural Progenitors and Birth Defect Formation in Rats
Cortical heterotopias are clusters of ectopic neurons in the brain, and are commonly associated with pharmaceutical resistant epilepsy in patients. We have previously characterized the robust penetrance of a cortical heterotopia in a rat model, induced by thyroid hormone (TH) disruption during gesta...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552232/ http://dx.doi.org/10.1210/js.2019-SAT-045 |