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SAT-045 Transient Developmental Hypothyroidism Results in Dysregulation of Neural Progenitors and Birth Defect Formation in Rats

Cortical heterotopias are clusters of ectopic neurons in the brain, and are commonly associated with pharmaceutical resistant epilepsy in patients. We have previously characterized the robust penetrance of a cortical heterotopia in a rat model, induced by thyroid hormone (TH) disruption during gesta...

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Detalles Bibliográficos
Autores principales:	O'Shaughnessy, Katherine, Thomas, Susan, Spring, Stephanie, Ford, Jermaine, Ford, Richard, Gilbert, Mary
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2019
Materias:	Non-Steroid Hormone Signaling
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552232/ http://dx.doi.org/10.1210/js.2019-SAT-045

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