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Rev-erbs and Glia—Implications for Neurodegenerative Diseases

Recently, we described a role for the circadian clock protein and nuclear receptor Rev-erbα in regulating glial activation states in the brain. Deletion of Rev-erbα resulted in microglial as well as astrocytic activation, while a Rev-erbα agonist diminished the severity of lipopolysaccharide (LPS)-i...

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Detalles Bibliográficos
Autores principales: Griffin, Percy, Dimitry, Julie M, Musiek, Erik S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552335/
https://www.ncbi.nlm.nih.gov/pubmed/31210735
http://dx.doi.org/10.1177/1179069519853233