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Carcinosarcoma of the breast: A case of breast conservation surgery and breast reconstruction

Breast carcinosarcoma is an extremely rare, clinically aggressive tumor, and no standard treatment has been established. We report about a 34-year-old woman presenting with a 2.5-cm-sized carcinosarcoma in her right breast. She presented to our hospital for examination of this mass. Ultrasonography...

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Autores principales: Kanaizumi, Hirofumi, Higashi, Chihiro, Tanaka, Yumiko, Hamada, Mika, Shinzaki, Wataru, Hashimoto, Yukihiko, Komoike, Yoshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552342/
https://www.ncbi.nlm.nih.gov/pubmed/31210937
http://dx.doi.org/10.1177/2050313X19853684
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author Kanaizumi, Hirofumi
Higashi, Chihiro
Tanaka, Yumiko
Hamada, Mika
Shinzaki, Wataru
Hashimoto, Yukihiko
Komoike, Yoshifumi
author_facet Kanaizumi, Hirofumi
Higashi, Chihiro
Tanaka, Yumiko
Hamada, Mika
Shinzaki, Wataru
Hashimoto, Yukihiko
Komoike, Yoshifumi
author_sort Kanaizumi, Hirofumi
collection PubMed
description Breast carcinosarcoma is an extremely rare, clinically aggressive tumor, and no standard treatment has been established. We report about a 34-year-old woman presenting with a 2.5-cm-sized carcinosarcoma in her right breast. She presented to our hospital for examination of this mass. Ultrasonography showed a hypoechoic mass with partially irregular margins. Fine-needle aspiration cytology indicated malignancy. No enlarged lymph nodes or distant metastases were detected. We diagnosed right breast cancer and performed partial mastectomy, sentinel lymph node biopsy, and latissimus dorsi muscle flap transfer. Histological findings revealed that the tumor consisted of a mixture of an epithelial component and a mesenchymal component. The final diagnosis was carcinosarcoma. After undergoing adjuvant chemotherapy and radiotherapy, the patient has had no recurrence, and her cosmesis is maintained. Clinical data of carcinosarcoma are insufficient. Breast conservation and reconstruction for carcinosarcoma may be suitable as local treatments; however, the most appropriate treatment method has not been established.
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spelling pubmed-65523422019-06-17 Carcinosarcoma of the breast: A case of breast conservation surgery and breast reconstruction Kanaizumi, Hirofumi Higashi, Chihiro Tanaka, Yumiko Hamada, Mika Shinzaki, Wataru Hashimoto, Yukihiko Komoike, Yoshifumi SAGE Open Med Case Rep Case Report Breast carcinosarcoma is an extremely rare, clinically aggressive tumor, and no standard treatment has been established. We report about a 34-year-old woman presenting with a 2.5-cm-sized carcinosarcoma in her right breast. She presented to our hospital for examination of this mass. Ultrasonography showed a hypoechoic mass with partially irregular margins. Fine-needle aspiration cytology indicated malignancy. No enlarged lymph nodes or distant metastases were detected. We diagnosed right breast cancer and performed partial mastectomy, sentinel lymph node biopsy, and latissimus dorsi muscle flap transfer. Histological findings revealed that the tumor consisted of a mixture of an epithelial component and a mesenchymal component. The final diagnosis was carcinosarcoma. After undergoing adjuvant chemotherapy and radiotherapy, the patient has had no recurrence, and her cosmesis is maintained. Clinical data of carcinosarcoma are insufficient. Breast conservation and reconstruction for carcinosarcoma may be suitable as local treatments; however, the most appropriate treatment method has not been established. SAGE Publications 2019-06-04 /pmc/articles/PMC6552342/ /pubmed/31210937 http://dx.doi.org/10.1177/2050313X19853684 Text en © The Author(s) 2019 http://www.creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Kanaizumi, Hirofumi
Higashi, Chihiro
Tanaka, Yumiko
Hamada, Mika
Shinzaki, Wataru
Hashimoto, Yukihiko
Komoike, Yoshifumi
Carcinosarcoma of the breast: A case of breast conservation surgery and breast reconstruction
title Carcinosarcoma of the breast: A case of breast conservation surgery and breast reconstruction
title_full Carcinosarcoma of the breast: A case of breast conservation surgery and breast reconstruction
title_fullStr Carcinosarcoma of the breast: A case of breast conservation surgery and breast reconstruction
title_full_unstemmed Carcinosarcoma of the breast: A case of breast conservation surgery and breast reconstruction
title_short Carcinosarcoma of the breast: A case of breast conservation surgery and breast reconstruction
title_sort carcinosarcoma of the breast: a case of breast conservation surgery and breast reconstruction
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552342/
https://www.ncbi.nlm.nih.gov/pubmed/31210937
http://dx.doi.org/10.1177/2050313X19853684
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