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SAT-009 Proof of Concept That Corticosterone Has a Higher Therapeutic Index Than Hydrocortisone in Patients with Congenital Adrenal Hyperplasia

Congenital adrenal hyperplasia (CAH) is associated with poor health outcomes. This is, in part, because doses of glucocorticoid which are sufficient to suppress excess adrenal androgens are also associated with adverse metabolic effects such as insulin resistance. This toxicity occurs with efficacio...

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Detalles Bibliográficos
Autores principales: Kyle, Catriona, Boyle, Luke, Nixon, Mark, Homer, Natalie, Andrew, Ruth, Freel, Marie, Stimson, Roland, Walker, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552504/
http://dx.doi.org/10.1210/js.2019-SAT-009