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SAT-LB036 Late Weaning Leads to Enrichment of Treg Cells Which Consequently Regulates Effector T Cell Responses in Peri-Pancreatic Lymph Nodes and Pancreas of Humanized Model T1D
The hallmark of type 1 diabetes (T1D) is immune-mediated destruction of insulin secreting β-cells in pancreatic islets. Children who progress to clinical T1D have detectable levels of islet-specific autoantibodies before age three. Early development of gut microbiota also has limited resilience and...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Endocrine Society
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552507/ http://dx.doi.org/10.1210/js.2019-SAT-LB036 |