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SAT-LB036 Late Weaning Leads to Enrichment of Treg Cells Which Consequently Regulates Effector T Cell Responses in Peri-Pancreatic Lymph Nodes and Pancreas of Humanized Model T1D

The hallmark of type 1 diabetes (T1D) is immune-mediated destruction of insulin secreting β-cells in pancreatic islets. Children who progress to clinical T1D have detectable levels of islet-specific autoantibodies before age three. Early development of gut microbiota also has limited resilience and...

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Detalles Bibliográficos
Autores principales:	Imam, Shahnawaz, Al-Khudhair, Ahmed, SALIM, NANCY, Lamendella, Regina, Jaume, Juan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2019
Materias:	Diabetes Mellitus and Glucose Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552507/ http://dx.doi.org/10.1210/js.2019-SAT-LB036

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