In-utero ultrasonography detection of fetal retinoblastoma and neonatal selective ophthalmic artery chemotherapy

We report a case of non-familial, sporadic fetal retinoblastoma (RB) that was accidently detected at 39 weeks of gestation on pre-natal ultrasonography in left eye (OS). Post-natal examination revealed Group A and, Group D RB in right eye (OD) and OS, respectively. At 35 days, selective ophthalmic a...

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Autores principales: Manjandavida, Fairooz P, Xia, Jiejun, Zhang, Jing, Tang, Xiao Yun, Yi, Hai Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552617/
https://www.ncbi.nlm.nih.gov/pubmed/31124531
http://dx.doi.org/10.4103/ijo.IJO_340_19
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author Manjandavida, Fairooz P
Xia, Jiejun
Zhang, Jing
Tang, Xiao Yun
Yi, Hai Rong
author_facet Manjandavida, Fairooz P
Xia, Jiejun
Zhang, Jing
Tang, Xiao Yun
Yi, Hai Rong
author_sort Manjandavida, Fairooz P
collection PubMed
description We report a case of non-familial, sporadic fetal retinoblastoma (RB) that was accidently detected at 39 weeks of gestation on pre-natal ultrasonography in left eye (OS). Post-natal examination revealed Group A and, Group D RB in right eye (OD) and OS, respectively. At 35 days, selective ophthalmic artery intra-arterial chemotherapy (IAC) was performed in OS and laser for OD. Pre-natal ultrasound and its application in RB are limited to those cases with a strong genetic predisposition. Our case was accidently detected at late gestation with no familial or genetic predisposition. In addition, this was the youngest reported case that received IAC on literature review.
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spelling pubmed-65526172019-06-13 In-utero ultrasonography detection of fetal retinoblastoma and neonatal selective ophthalmic artery chemotherapy Manjandavida, Fairooz P Xia, Jiejun Zhang, Jing Tang, Xiao Yun Yi, Hai Rong Indian J Ophthalmol Case Reports We report a case of non-familial, sporadic fetal retinoblastoma (RB) that was accidently detected at 39 weeks of gestation on pre-natal ultrasonography in left eye (OS). Post-natal examination revealed Group A and, Group D RB in right eye (OD) and OS, respectively. At 35 days, selective ophthalmic artery intra-arterial chemotherapy (IAC) was performed in OS and laser for OD. Pre-natal ultrasound and its application in RB are limited to those cases with a strong genetic predisposition. Our case was accidently detected at late gestation with no familial or genetic predisposition. In addition, this was the youngest reported case that received IAC on literature review. Wolters Kluwer - Medknow 2019-06 /pmc/articles/PMC6552617/ /pubmed/31124531 http://dx.doi.org/10.4103/ijo.IJO_340_19 Text en Copyright: © 2019 Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Reports
Manjandavida, Fairooz P
Xia, Jiejun
Zhang, Jing
Tang, Xiao Yun
Yi, Hai Rong
In-utero ultrasonography detection of fetal retinoblastoma and neonatal selective ophthalmic artery chemotherapy
title In-utero ultrasonography detection of fetal retinoblastoma and neonatal selective ophthalmic artery chemotherapy
title_full In-utero ultrasonography detection of fetal retinoblastoma and neonatal selective ophthalmic artery chemotherapy
title_fullStr In-utero ultrasonography detection of fetal retinoblastoma and neonatal selective ophthalmic artery chemotherapy
title_full_unstemmed In-utero ultrasonography detection of fetal retinoblastoma and neonatal selective ophthalmic artery chemotherapy
title_short In-utero ultrasonography detection of fetal retinoblastoma and neonatal selective ophthalmic artery chemotherapy
title_sort in-utero ultrasonography detection of fetal retinoblastoma and neonatal selective ophthalmic artery chemotherapy
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552617/
https://www.ncbi.nlm.nih.gov/pubmed/31124531
http://dx.doi.org/10.4103/ijo.IJO_340_19
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