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SUN-543 Myostatin Inhibits IGF1-Dependent Citrate Production during Osteogenesis in a Mouse Mesenchymal Stem Cell Line
Bone formation and osteoblast activation require glucose. Citrate is a key intermediate in the tricarboxylic acid (TCA) cycle that is the major energy-yielding metabolic pathway in cells. Citrate homeostasis, therefore, is critically important for glucose metabolism and energy production. In additio...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552799/ http://dx.doi.org/10.1210/js.2019-SUN-543 |