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SUN-543 Myostatin Inhibits IGF1-Dependent Citrate Production during Osteogenesis in a Mouse Mesenchymal Stem Cell Line

Bone formation and osteoblast activation require glucose. Citrate is a key intermediate in the tricarboxylic acid (TCA) cycle that is the major energy-yielding metabolic pathway in cells. Citrate homeostasis, therefore, is critically important for glucose metabolism and energy production. In additio...

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Detalles Bibliográficos
Autores principales: Liu, Xin-Hua, Pan, Jiangping, Bauman, Williams, Cardozo, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552799/
http://dx.doi.org/10.1210/js.2019-SUN-543