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SUN-024 Uncovering a Novel Role for Nuclear Receptor Fxr and Shp in Regulating N-Linked Glycosylation
Nuclear receptor Farnesoid X Receptor (Fxr) and Small Heterodimer Partner (Shp) are key regulators of glucose, fat and bile acid homeostasis. As expected, liver-specific deletion of both Fxr and Shp (LDKO) sensitizes mice to bile acid excess. Surprisingly, high throughput RNA-sequencing analysis rev...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Endocrine Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552847/ http://dx.doi.org/10.1210/js.2019-SUN-024 |