Light chain lambda myeloma with fatal AL cardiac amyloidosis in a 21‐year‐old patient: A case report and review

Multi‐organ AL amyloidosis is a therapeutic challenge because of light chain deposits severely damaging the function of concerned organs. Cardiac involvement, which leads to concentric hypertrophy of both ventricles, is particularly severe and leads to poor prognosis regardless of combination chemot...

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Autores principales: Camus, Vincent, Dubois, Sydney, Thiébaut, Pierre‐Alain, Lepretre, Stéphane, Lenain, Pascal, Picquenot, Jean‐Michel, Veresezan, Elena‐Liana, François, Arnaud, Penther, Dominique, Bauer, Fabrice, Jaccard, Arnaud, Jardin, Fabrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552948/
https://www.ncbi.nlm.nih.gov/pubmed/31183088
http://dx.doi.org/10.1002/ccr3.2165
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author Camus, Vincent
Dubois, Sydney
Thiébaut, Pierre‐Alain
Lepretre, Stéphane
Lenain, Pascal
Picquenot, Jean‐Michel
Veresezan, Elena‐Liana
François, Arnaud
Penther, Dominique
Bauer, Fabrice
Jaccard, Arnaud
Jardin, Fabrice
author_facet Camus, Vincent
Dubois, Sydney
Thiébaut, Pierre‐Alain
Lepretre, Stéphane
Lenain, Pascal
Picquenot, Jean‐Michel
Veresezan, Elena‐Liana
François, Arnaud
Penther, Dominique
Bauer, Fabrice
Jaccard, Arnaud
Jardin, Fabrice
author_sort Camus, Vincent
collection PubMed
description Multi‐organ AL amyloidosis is a therapeutic challenge because of light chain deposits severely damaging the function of concerned organs. Cardiac involvement, which leads to concentric hypertrophy of both ventricles, is particularly severe and leads to poor prognosis regardless of combination chemotherapy. This case pinpoints the relevance of combining clinical, histological, and echocardiographic information in the management of this complex and life‐threatening disease.
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spelling pubmed-65529482019-06-10 Light chain lambda myeloma with fatal AL cardiac amyloidosis in a 21‐year‐old patient: A case report and review Camus, Vincent Dubois, Sydney Thiébaut, Pierre‐Alain Lepretre, Stéphane Lenain, Pascal Picquenot, Jean‐Michel Veresezan, Elena‐Liana François, Arnaud Penther, Dominique Bauer, Fabrice Jaccard, Arnaud Jardin, Fabrice Clin Case Rep Case Reports Multi‐organ AL amyloidosis is a therapeutic challenge because of light chain deposits severely damaging the function of concerned organs. Cardiac involvement, which leads to concentric hypertrophy of both ventricles, is particularly severe and leads to poor prognosis regardless of combination chemotherapy. This case pinpoints the relevance of combining clinical, histological, and echocardiographic information in the management of this complex and life‐threatening disease. John Wiley and Sons Inc. 2019-05-07 /pmc/articles/PMC6552948/ /pubmed/31183088 http://dx.doi.org/10.1002/ccr3.2165 Text en © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Camus, Vincent
Dubois, Sydney
Thiébaut, Pierre‐Alain
Lepretre, Stéphane
Lenain, Pascal
Picquenot, Jean‐Michel
Veresezan, Elena‐Liana
François, Arnaud
Penther, Dominique
Bauer, Fabrice
Jaccard, Arnaud
Jardin, Fabrice
Light chain lambda myeloma with fatal AL cardiac amyloidosis in a 21‐year‐old patient: A case report and review
title Light chain lambda myeloma with fatal AL cardiac amyloidosis in a 21‐year‐old patient: A case report and review
title_full Light chain lambda myeloma with fatal AL cardiac amyloidosis in a 21‐year‐old patient: A case report and review
title_fullStr Light chain lambda myeloma with fatal AL cardiac amyloidosis in a 21‐year‐old patient: A case report and review
title_full_unstemmed Light chain lambda myeloma with fatal AL cardiac amyloidosis in a 21‐year‐old patient: A case report and review
title_short Light chain lambda myeloma with fatal AL cardiac amyloidosis in a 21‐year‐old patient: A case report and review
title_sort light chain lambda myeloma with fatal al cardiac amyloidosis in a 21‐year‐old patient: a case report and review
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552948/
https://www.ncbi.nlm.nih.gov/pubmed/31183088
http://dx.doi.org/10.1002/ccr3.2165
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