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SUN-470 The Homeodomain Transcription Factors Six3 and OTX2 Act on Mouse and Human Kisspeptin Promoters to Repress Transcription

Idiopathic hypogonadotropic hypogonadism (IHH) is a gonadotropin-releasing hormone (GnRH) deficiency disorder that, in a subset of individuals, can occur alongside anosmia (Kallmann Syndrome). Known genetic causes for these disorders account for only 45% of affected individuals, leaving the majority...

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Detalles Bibliográficos
Autores principales: Newton, Shanna, Mellon, Pamela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553074/
http://dx.doi.org/10.1210/js.2019-SUN-470

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