SUN-082 The Impact of Gender on Inpatient Mortality of Hypertensive Latino Patients Across CKD Stage 3 to ESRD in the United States

BACKGROUND: Hypertension and chronic kidney disease are two of the most important risk factors for cardiovascular disease, a major cause of death in the US population. The impact of gender in this equation remains unclear, more so, on how it affects the Hispanic population. Studies comparing the outcomes and difference in inpatient mortality between male and female with hypertension and CKD are sparse. Our aim was to determine if gender in Latino population affect the inpatient survival rate among hypertensive patients across different CKD stages. METHODS: Data was extracted from the 2005 to 2012 Nationwide Inpatient Sample (NIS). Using propensity score matching, female hypertensive with chronic kidney disease (stage 3, 4, 5 or ESRD) patients were matched with hypertensive males at a 1:1 ratio. We compared inpatient mortality, both crude mortality and mortality per CKD stage, length of stay and total hospital charges between male and females. Analyses were performed using SAS version 9.3 (SAS Institute, Cary, NC, USA). RESULTS: Among 227,923 hospitalized hypertensive patients, 118,132 (51.83%) were males and 109,791 (48.17%) females. 18.76%, 10.31%, 3.85% and 67.17% were Females with CKD 3 to ESRD respectively. Males across CKD stages 3 to ESRD were 19.47%, 9.54%, 3.63% and 67.43% respectively. In-hospital crude mortality was significantly higher for males compared to group of females before match, (3.89 vs 3.74 p= 0.05), interestingly, mortality was higher after match for females (3.85 vs 3.79 p= 0.48). Mean length of stay for hypertensive females were significantly higher than males, irrespective of CKD stage (6.74 vs 6.70 days, p= 0.001), however at the male group had an expense of higher hospital charges (63,686 vs 61,667 dollars, p= 0.001). CONCLUSION: Latino hypertensive men with any stage of CKD are more at risk of dying then their counterpart women and have higher hospital charges. Further studies are needed to explore these associated genders in difference outcomes in this population.