SUN-264 Mutations in the Maternally Imprinted Genes, MKRN3 and DLK1, Associated with Central Precocious Puberty

Context: Central precocious puberty (CPP) results from premature activation of the hypothalamic–pituitary–gonadal axis. Loss-of-function mutations in makorin ring finger 3 (MKRN3), a maternally imprinted gene, have been recognized as the most common genetic cause of CPP. More recently, a complex def...

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Detalles Bibliográficos
Autores principales: Abreu, Ana Paula, Garcia, Leonardo, Pereira, Sidney, Macedo, Delanie, Magnusson, Melissa, Gagliardi, Priscila, Tütüncüler, Filiz, Bird, Keisha, Lofrano-Porto, Adriana, Roberts, Stephanie, Carroll, Rona, Latronico, Ana Claudia, Kaiser, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Pediatric Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553159/
http://dx.doi.org/10.1210/js.2019-SUN-264

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