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SUN-087 Effects of Leptin Replacement on Circulating Plasma Inhibitors of Lipoprotein Lipase in Patients with Lipodystrophy

Lipodystrophy syndromes (LD) result from selective deficiency of adipose tissue, leading to low leptin. Low leptin leads to hyperphagia and ectopic lipid storage, causing severe insulin resistance and metabolic complications including high triglycerides (TG) and subsequent pancreatitis. Replacement...

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Detalles Bibliográficos
Autores principales: Lightbourne, Marissa, Wolska, Anna, Remaley, Alan, Walter, Mary, Muniyappa, Ranganath, Rother, Kristina, Brown, Rebecca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553279/
http://dx.doi.org/10.1210/js.2019-SUN-087