SUN-012 Investigating the Effect of GRHL2 on pS118-ER Transcriptional Activity in Breast Cancer

In estrogen receptor (ER) positive breast cancers, there is a continual balance between growth and differentiation. Upon activation with estrogen, ER is phosphorylated at serine 118 (pS118-ER). High pS118-ER expression has been observed in low grade and well differentiated tumors. However, this phos...

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Detalles Bibliográficos
Autores principales: Reese, Rebecca, Helzer, Kyle, Morgan, Molly, Beebe, David, Alarid, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Steroid Hormones and Receptors
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553404/
http://dx.doi.org/10.1210/js.2019-SUN-012

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