Cargando…

Mitochondrial fusion is required for regulation of mitochondrial DNA replication

Mitochondrial dynamics is an essential physiological process controlling mitochondrial content mixing and mobility to ensure proper function and localization of mitochondria at intracellular sites of high-energy demand. Intriguingly, for yet unknown reasons, severe impairment of mitochondrial fusion...

Descripción completa

Detalles Bibliográficos
Autores principales:	Silva Ramos, Eduardo, Motori, Elisa, Brüser, Christian, Kühl, Inge, Yeroslaviz, Assa, Ruzzenente, Benedetta, Kauppila, Johanna H. K., Busch, Jakob D., Hultenby, Kjell, Habermann, Bianca H., Jakobs, Stefan, Larsson, Nils-Göran, Mourier, Arnaud
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553695/ https://www.ncbi.nlm.nih.gov/pubmed/31170154 http://dx.doi.org/10.1371/journal.pgen.1008085

Ejemplares similares

Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels
por: Mourier, Arnaud, et al.
Publicado: (2015)

The Bicoid Stability Factor Controls Polyadenylation and Expression of Specific Mitochondrial mRNAs in Drosophila melanogaster
por: Bratic, Ana, et al.
Publicado: (2011)

Drosophila melanogaster LRPPRC2 is involved in coordination of mitochondrial translation
por: Baggio, Francesca, et al.
Publicado: (2014)

TWINKLE is an essential mitochondrial helicase required for synthesis of nascent D-loop strands and complete mtDNA replication
por: Milenkovic, Dusanka, et al.
Publicado: (2013)

SLIRP Regulates the Rate of Mitochondrial Protein Synthesis and Protects LRPPRC from Degradation
por: Lagouge, Marie, et al.
Publicado: (2015)

Tracing the Trail of Protons through Complex I of the Mitochondrial Respiratory Chain
por: Mourier, Arnaud, et al.
Publicado: (2011)

Loss of LRPPRC causes ATP synthase deficiency
por: Mourier, Arnaud, et al.
Publicado: (2014)

The Respiratory Chain Supercomplex Organization Is Independent of COX7a2l Isoforms
por: Mourier, Arnaud, et al.
Publicado: (2014)

Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals
por: Kühl, Inge, et al.
Publicado: (2017)

MTERF3 Regulates Mitochondrial Ribosome Biogenesis in Invertebrates and Mammals
por: Wredenberg, Anna, et al.
Publicado: (2013)

NSUN4 Is a Dual Function Mitochondrial Protein Required for Both Methylation of 12S rRNA and Coordination of Mitoribosomal Assembly
por: Metodiev, Metodi Dimitrov, et al.
Publicado: (2014)

LRPPRC-mediated folding of the mitochondrial transcriptome
por: Siira, Stefan J., et al.
Publicado: (2017)

The cytoplasmic poly(A) polymerases GLD-2 and GLD-4 promote general gene expression via distinct mechanisms
por: Nousch, Marco, et al.
Publicado: (2014)

Changes of mitochondrial ultrastructure and function during ageing in mice and Drosophila
por: Brandt, Tobias, et al.
Publicado: (2017)

A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease
por: Kauppila, Johanna H.K., et al.
Publicado: (2016)

Mitochondrial phosphoproteomes are functionally specialized across tissues
por: Hansen, Fynn M, et al.
Publicado: (2023)

High levels of TFAM repress mammalian mitochondrial DNA transcription in vivo
por: Bonekamp, Nina A, et al.
Publicado: (2021)

The complete and fully assembled genome sequence of Aeromonas salmonicida subsp. pectinolytica and its comparative analysis with other Aeromonas species: investigation of the mobilome in environmental and pathogenic strains
por: Pfeiffer, Friedhelm, et al.
Publicado: (2018)

Genome-wide RNAi screen for regulators of UPR(mt) in Caenorhabditis elegans mutants with defects in mitochondrial fusion
por: Haeussler, Simon, et al.
Publicado: (2021)

Reweaving the Fabric of Mitochondrial Contact Sites in Astrocytes
por: Bergami, Matteo, et al.
Publicado: (2020)

Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice
por: Kauppila, Johanna H K, et al.
Publicado: (2018)

Mutations of mitochondrial DNA are not major contributors to aging of fruit flies
por: Kauppila, Timo E. S., et al.
Publicado: (2018)

Mitochondrial DNA mutations in disease and aging
por: Park, Chan Bae, et al.
Publicado: (2011)

Loss of UCP2 Attenuates Mitochondrial Dysfunction without Altering ROS Production and Uncoupling Activity
por: Kukat, Alexandra, et al.
Publicado: (2014)

The RNA-binding protein Arrest (Bruno) regulates alternative splicing to enable myofibril maturation in Drosophila flight muscle
por: Spletter, Maria L, et al.
Publicado: (2015)

Mic10 Oligomerization Pinches off Mitochondrial Cristae
por: Milenkovic, Dusanka, et al.
Publicado: (2015)

POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA
por: Kühl, Inge, et al.
Publicado: (2016)

The Leucine-rich Pentatricopeptide Repeat-containing Protein (LRPPRC) Does Not Activate Transcription in Mammalian Mitochondria
por: Harmel, Julia, et al.
Publicado: (2013)

A transcriptomics resource reveals a transcriptional transition during ordered sarcomere morphogenesis in flight muscle
por: Spletter, Maria L, et al.
Publicado: (2018)

Neuronal metabolic rewiring promotes resilience to neurodegeneration caused by mitochondrial dysfunction
por: Motori, E., et al.
Publicado: (2020)

Bax assembles into large ring‐like structures remodeling the mitochondrial outer membrane in apoptosis
por: Große, Lena, et al.
Publicado: (2016)

Stage-specific combinations of opposing poly(A) modifying enzymes guide gene expression during early oogenesis
por: Nousch, Marco, et al.
Publicado: (2019)

Complementation between polymerase- and exonuclease-deficient mitochondrial DNA polymerase mutants in genomically engineered flies
por: Bratic, Ana, et al.
Publicado: (2015)

Mitochondrial DNA copy number in human disease: the more the better?
por: Filograna, Roberta, et al.
Publicado: (2020)

Ret rescues mitochondrial morphology and muscle degeneration of Drosophila Pink1 mutants
por: Klein, Pontus, et al.
Publicado: (2014)

MICOS coordinates with respiratory complexes and lipids to establish mitochondrial inner membrane architecture
por: Friedman, Jonathan R, et al.
Publicado: (2015)

Strong Purifying Selection in Transmission of Mammalian Mitochondrial DNA
por: Stewart, James Bruce, et al.
Publicado: (2008)

The mitoXplorer 2.0 update: integrating and interpreting mitochondrial expression dynamics within a cellular context
por: Marchiano, Fabio, et al.
Publicado: (2022)

Ultra-Deep Sequencing of Mouse Mitochondrial DNA: Mutational Patterns and Their Origins
por: Ameur, Adam, et al.
Publicado: (2011)

Maintenance of mitochondrial DNA copy number is essential for osteoclast survival
por: Miyazaki, Tsuyoshi, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_vqlk51mitqhfc3hlulh7r4s7e8