Comprehensive molecular pharmacology screening reveals potential new receptor interactions for clinically relevant opioids

Most clinically used opioids are thought to induce analgesia through activation of the mu opioid receptor (MOR). However, disparities have been observed between the efficacy of opioids in activating the MOR in vitro and in inducing analgesia in vivo. In addition, some clinically used opioids do not...

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Detalles Bibliográficos
Autores principales: Olson, Keith M., Duron, David I., Womer, Daniel, Fell, Ryan, Streicher, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553708/
https://www.ncbi.nlm.nih.gov/pubmed/31170174
http://dx.doi.org/10.1371/journal.pone.0217371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553708/
https://www.ncbi.nlm.nih.gov/pubmed/31170174
http://dx.doi.org/10.1371/journal.pone.0217371

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