The formyl peptide receptor agonist FPRa14 induces differentiation of Neuro2a mouse neuroblastoma cells into multiple distinct morphologies which can be specifically inhibited with FPR antagonists and FPR knockdown using siRNA

The N-formyl peptide receptors (FPRs) have been identified within neuronal tissues and may serve as yet undetermined functions within the nervous system. The FPRs have been implicated in the progression and invasiveness of neuroblastoma and other cancers. In this study the effects of the synthetic F...

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Detalles Bibliográficos
Autores principales: Cussell, Peter J. G., Howe, Michael S., Illingworth, Thomas A., Gomez Escalada, Margarita, Milton, Nathaniel G. N., Paterson, Andrew W. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553754/
https://www.ncbi.nlm.nih.gov/pubmed/31170199
http://dx.doi.org/10.1371/journal.pone.0217815

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