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Primary infection by Pneumocystis induces Notch-independent Clara cell mucin production in rat distal airways
Clara cells are the main airway secretory cells able to regenerate epithelium in the distal airways through transdifferentiating into goblet cells, a process under negative regulation of the Notch pathway. Pneumocystis is a highly prevalent fungus in humans occurring between 2 and 5 months of age, a...
Autores principales: | Méndez, Andrea, Rojas, Diego A., Ponce, Carolina A., Bustamante, Rebeca, Beltrán, Caroll J., Toledo, Jorge, García-Angulo, Victor A., Henriquez, Mauricio, Vargas, Sergio L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553854/ https://www.ncbi.nlm.nih.gov/pubmed/31170201 http://dx.doi.org/10.1371/journal.pone.0217684 |
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