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Endothelial Cells Regulate Physiological Cardiomyocyte Growth via VEGFR2-Mediated Paracrine Signaling
BACKGROUND: Heart failure, which is a major global health problem, is often preceded by pathological cardiac hypertrophy. The expansion of the cardiac vasculature, to maintain adequate supply of oxygen and nutrients, is a key determinant of whether the heart grows in a physiological compensated mann...
Autores principales: | Kivelä, Riikka, Hemanthakumar, Karthik Amudhala, Vaparanta, Katri, Robciuc, Marius, Izumiya, Yasuhiro, Kidoya, Hiroyasu, Takakura, Nobuyuki, Peng, Xuyang, Sawyer, Douglas B., Elenius, Klaus, Walsh, Kenneth, Alitalo, Kari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553980/ https://www.ncbi.nlm.nih.gov/pubmed/30922063 http://dx.doi.org/10.1161/CIRCULATIONAHA.118.036099 |
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