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Exonuclease Requirements for Mammalian Ribosomal RNA Biogenesis and Surveillance
Ribosomal RNA (rRNA) biogenesis is a multistep process requiring several nuclear and cytoplasmic exonucleases. The exact processing steps for mammalian 5.8S rRNA remain obscure. Here, using loss-of-function approaches in mouse embryonic stem cells and deep sequencing of rRNA intermediates, we invest...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554070/ https://www.ncbi.nlm.nih.gov/pubmed/31160785 http://dx.doi.org/10.1038/s41594-019-0234-x |