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Diagnostic value and safety of color doppler ultrasound-guided transthoracic core needle biopsy of thoracic disease

Objective: The aim of the present study was to explore the diagnostic value and safety of color Doppler ultrasound (US)-guided transthoracic core needle biopsy (CNB) of peripheral lung, chest wall and mediastinal lesions using automated biopsy guns. Materials and methods: We analyzed clinical and im...

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Autores principales: Huang, Weina, Chen, Libin, Xu, Ning, Wang, Linfeng, Liu, Fang, He, Shiyi, Lai, Tianwen, Chen, Xueqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554213/
https://www.ncbi.nlm.nih.gov/pubmed/31127026
http://dx.doi.org/10.1042/BSR20190104
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author Huang, Weina
Chen, Libin
Xu, Ning
Wang, Linfeng
Liu, Fang
He, Shiyi
Lai, Tianwen
Chen, Xueqin
author_facet Huang, Weina
Chen, Libin
Xu, Ning
Wang, Linfeng
Liu, Fang
He, Shiyi
Lai, Tianwen
Chen, Xueqin
author_sort Huang, Weina
collection PubMed
description Objective: The aim of the present study was to explore the diagnostic value and safety of color Doppler ultrasound (US)-guided transthoracic core needle biopsy (CNB) of peripheral lung, chest wall and mediastinal lesions using automated biopsy guns. Materials and methods: We analyzed clinical and image data, histopathologic and microbiologic details and complications from 121 patients with peripheral lung, chest wall and mediastinal lesions who underwent color Doppler US-guided transthoracic CNB in Ningbo First Hospital between January 2015 and June 2018. Results: Color Doppler US-guided transthoracic CNB performed with a freehand technique using automated biopsy guns had a sensitivity of 93.94%, a specificity of 100%, a positive predictive value of 100%, a negative predictive value of 78.57%, and a diagnostic accuracy of 95.04%. Lesion size did not affect the diagnostic rate (P=0.40). No serious complications of the procedure were noted. Conclusion: Color Doppler US-guided transthoracic CNB of peripheral lung, chest wall and mediastinal lesions is a safe and inexpensive procedure. The diagnostic accuracy of color Doppler US-guided transthoracic CNB was higher than that of color Doppler US-guided transthoracic fine needle aspiration biopsy (FNAB).
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spelling pubmed-65542132019-06-19 Diagnostic value and safety of color doppler ultrasound-guided transthoracic core needle biopsy of thoracic disease Huang, Weina Chen, Libin Xu, Ning Wang, Linfeng Liu, Fang He, Shiyi Lai, Tianwen Chen, Xueqin Biosci Rep Research Articles Objective: The aim of the present study was to explore the diagnostic value and safety of color Doppler ultrasound (US)-guided transthoracic core needle biopsy (CNB) of peripheral lung, chest wall and mediastinal lesions using automated biopsy guns. Materials and methods: We analyzed clinical and image data, histopathologic and microbiologic details and complications from 121 patients with peripheral lung, chest wall and mediastinal lesions who underwent color Doppler US-guided transthoracic CNB in Ningbo First Hospital between January 2015 and June 2018. Results: Color Doppler US-guided transthoracic CNB performed with a freehand technique using automated biopsy guns had a sensitivity of 93.94%, a specificity of 100%, a positive predictive value of 100%, a negative predictive value of 78.57%, and a diagnostic accuracy of 95.04%. Lesion size did not affect the diagnostic rate (P=0.40). No serious complications of the procedure were noted. Conclusion: Color Doppler US-guided transthoracic CNB of peripheral lung, chest wall and mediastinal lesions is a safe and inexpensive procedure. The diagnostic accuracy of color Doppler US-guided transthoracic CNB was higher than that of color Doppler US-guided transthoracic fine needle aspiration biopsy (FNAB). Portland Press Ltd. 2019-06-07 /pmc/articles/PMC6554213/ /pubmed/31127026 http://dx.doi.org/10.1042/BSR20190104 Text en © 2019 The Author(s). http://creativecommons.org/licenses/by/4.0/This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) (http://creativecommons.org/licenses/by/4.0/) .
spellingShingle Research Articles
Huang, Weina
Chen, Libin
Xu, Ning
Wang, Linfeng
Liu, Fang
He, Shiyi
Lai, Tianwen
Chen, Xueqin
Diagnostic value and safety of color doppler ultrasound-guided transthoracic core needle biopsy of thoracic disease
title Diagnostic value and safety of color doppler ultrasound-guided transthoracic core needle biopsy of thoracic disease
title_full Diagnostic value and safety of color doppler ultrasound-guided transthoracic core needle biopsy of thoracic disease
title_fullStr Diagnostic value and safety of color doppler ultrasound-guided transthoracic core needle biopsy of thoracic disease
title_full_unstemmed Diagnostic value and safety of color doppler ultrasound-guided transthoracic core needle biopsy of thoracic disease
title_short Diagnostic value and safety of color doppler ultrasound-guided transthoracic core needle biopsy of thoracic disease
title_sort diagnostic value and safety of color doppler ultrasound-guided transthoracic core needle biopsy of thoracic disease
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554213/
https://www.ncbi.nlm.nih.gov/pubmed/31127026
http://dx.doi.org/10.1042/BSR20190104
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