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Targeted Oligonucleotides for Treating Neurodegenerative Tandem Repeat Diseases
Nucleotide repeat disorders encompass more than 30 diseases, most of which show dominant inheritance, such as Huntington’s disease, spinocerebellar ataxias, and myotonic dystrophies. Yet others, including Friedreich’s ataxia, are recessively inherited. A common feature is the presence of a DNA tande...
Autores principales: | Zain, Rula, Smith, C. I. Edvard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554256/ https://www.ncbi.nlm.nih.gov/pubmed/31098852 http://dx.doi.org/10.1007/s13311-019-00712-9 |
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