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Sentinel lymph node biopsy in cN0 neck management of parotid cancer

Our goals was to evaluate how sentinel lymph node biopsy (SLNB) benefit neck management in patients with parotid cancer. Patients diagnosed with cN0 parotid cancer by preoperative fine needle puncture were prospectively enrolled. The neck status was evaluated by SLNB. If node metastasis was proved b...

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Autores principales: Pan, Wenting, Ba, Kai, Niu, Xingyu, Liu, Fei, Fang, Qigen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554268/
https://www.ncbi.nlm.nih.gov/pubmed/31171810
http://dx.doi.org/10.1038/s41598-019-44790-3
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author Pan, Wenting
Ba, Kai
Niu, Xingyu
Liu, Fei
Fang, Qigen
author_facet Pan, Wenting
Ba, Kai
Niu, Xingyu
Liu, Fei
Fang, Qigen
author_sort Pan, Wenting
collection PubMed
description Our goals was to evaluate how sentinel lymph node biopsy (SLNB) benefit neck management in patients with parotid cancer. Patients diagnosed with cN0 parotid cancer by preoperative fine needle puncture were prospectively enrolled. The neck status was evaluated by SLNB. If node metastasis was proved by SLNB, a neck dissection of level I–V a was performed, or a wait-and-see policy was conducted for the patient. All related information was extracted and analyzed. Positive SLNB result occurred in 33 (16.7%) patients, and level II metastasis was noted in 100% of the patients. Isolated level III metastasis was noted in 3 (9.1%) patients. During our follow-up with mean time of 49.5 months, 20 patients developed regional recurrence, in which 6 patients had neck dissection as part of their initial management. All the recurrent neck disease was successfully salvaged. Therefore, SLNB was a reliable procedure for neck management in parotid cancer.
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spelling pubmed-65542682019-06-14 Sentinel lymph node biopsy in cN0 neck management of parotid cancer Pan, Wenting Ba, Kai Niu, Xingyu Liu, Fei Fang, Qigen Sci Rep Article Our goals was to evaluate how sentinel lymph node biopsy (SLNB) benefit neck management in patients with parotid cancer. Patients diagnosed with cN0 parotid cancer by preoperative fine needle puncture were prospectively enrolled. The neck status was evaluated by SLNB. If node metastasis was proved by SLNB, a neck dissection of level I–V a was performed, or a wait-and-see policy was conducted for the patient. All related information was extracted and analyzed. Positive SLNB result occurred in 33 (16.7%) patients, and level II metastasis was noted in 100% of the patients. Isolated level III metastasis was noted in 3 (9.1%) patients. During our follow-up with mean time of 49.5 months, 20 patients developed regional recurrence, in which 6 patients had neck dissection as part of their initial management. All the recurrent neck disease was successfully salvaged. Therefore, SLNB was a reliable procedure for neck management in parotid cancer. Nature Publishing Group UK 2019-06-06 /pmc/articles/PMC6554268/ /pubmed/31171810 http://dx.doi.org/10.1038/s41598-019-44790-3 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Pan, Wenting
Ba, Kai
Niu, Xingyu
Liu, Fei
Fang, Qigen
Sentinel lymph node biopsy in cN0 neck management of parotid cancer
title Sentinel lymph node biopsy in cN0 neck management of parotid cancer
title_full Sentinel lymph node biopsy in cN0 neck management of parotid cancer
title_fullStr Sentinel lymph node biopsy in cN0 neck management of parotid cancer
title_full_unstemmed Sentinel lymph node biopsy in cN0 neck management of parotid cancer
title_short Sentinel lymph node biopsy in cN0 neck management of parotid cancer
title_sort sentinel lymph node biopsy in cn0 neck management of parotid cancer
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554268/
https://www.ncbi.nlm.nih.gov/pubmed/31171810
http://dx.doi.org/10.1038/s41598-019-44790-3
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