Modeling the Effect of the Metastatic Microenvironment on Phenotypes Conferred by Estrogen Receptor Mutations Using a Human Liver Microphysiological System

Reciprocal coevolution of tumors and their microenvironments underlies disease progression, yet intrinsic limitations of patient-derived xenografts and simpler cell-based models present challenges towards a deeper understanding of these intercellular communication networks. To help overcome these ba...

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Detalles Bibliográficos
Autores principales: Miedel, Mark T., Gavlock, Dillon C., Jia, Shanhang, Gough, Albert, Taylor, D. Lansing, Stern, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554298/
https://www.ncbi.nlm.nih.gov/pubmed/31171849
http://dx.doi.org/10.1038/s41598-019-44756-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554298/
https://www.ncbi.nlm.nih.gov/pubmed/31171849
http://dx.doi.org/10.1038/s41598-019-44756-5

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